Sailor Moon is the star of the show. Her name is Serena, and she is destined to save the universe. While attending Crossroads Junior High, Serena is visited by a cat with the power to speak: Luna. Luna befriends Serena and gives her a brooch that allows her to tap the power of the Emperium by saying the words "Moon Prism Power!" When these words are uttered, Serena becomes Sailor Moon, champion of goodness.

Serena has problems at first adjusting to the differences between high school and being a pretty soldier. But she finds strength in her friends, particularly her best friend Raye, who becomes Sailor Mars. Raye and Serena fight all the time but are very close. Gradually, the Sailor scouts form, and it is at that point that Serena's true destiny begins to unfold…