Sailor Moon is the story of Serena, a junior high school student who discovers that she has mystical powers and is destined to protect the world from the evil Queen Beryl and the fiends of the Negaverse.

Gradually, Serena assembles a team of Sailor Scouts to help her battle the forces of darkness in the name of Queen Serenity of the Emperium. Sailor Moon, Sailor Mercury, Sailor Mars, Sailor Venus and Sailor Jupiter form the main components of the team. Sailor Moon is first given her powers by her cat, Luna, who was a trusted advisor of Queen Serenity, and sticks with her through thick and thin.

The Sailor Scouts must take on the dwellers of the Negaverse while dealing with the problems of adolescence at the same time. Bad grades and crushes at Crossroads Junior High can be just as perplexing as the forces of evil: it's not easy being a pretty soldier. All the while, Serena moves slowly towards her destiny, to save the universe as Neo–Queen Serenity in the name of the Moon. This is the story of the one called Sailor Moon.