Cialis ®
About Cialis (tadalafil)?
Cialis is in a class of medications known as PDE-5 inhibitors, these are used to treat cases of male impotence. Elli Lilly and Icos are currently marketing Cialis in the USA, UK and other European countries.
How does Cialis (tadalafil) work?
Cialis acts in exactly the same way as Viagra, by blocking an enzyme called phosphodiesterase-5, or PDE-5. This helps the smooth muscles in the penis relax and widen, which allows for more blood to enter. As a result, you gain erections faster and easier with Cialis.
How well does Cialis (tadalafil) work?
Cialis is approved in these markets for the treatment of mild to severe ED at both 10 and 20 mg doses. The labels in each of these markets indicate that the product should be taken prior to anticipated sexual activity and without regard to food. Just like Viagra, sexual stimulation is needed for Cialis to work. According to the European label, the efficacy of Cialis may persist up to 24 hours after the pill is taken.
Cialis Clinical Data Overview
More than 4,000 men have participated in more than 60 studies that characterized the safety and efficacy profile of Cialis. In primary efficacy studies involving 1,112 men (804 Cialis, 308 placebo) with mild to severe ED, up to 81 percent of those treated with Cialis reported improved erections compared with 35 percent of those taking placebo(1).
The most commonly reported adverse events were headache, upset stomach, nasal congestion, backache, muscle ache, dizziness, and flushing. The adverse events reported with Cialis were transient and generally mild or moderate. As with other PDE5 inhibitors, the use of Cialis is contraindicated in patients who are taking nitrates. It should not be taken by patients with certain heart diseases for whom sexual activity itself is not advisable.
Remember that no medicine is for everyone. If you take any form of nitrates, often prescribed to control chest pains, do not take Cialis. This combination could cause an unsafe drop in blood pressure. |
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